Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics.
Identifieur interne : 000100 ( Main/Exploration ); précédent : 000099; suivant : 000101Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics.
Auteurs : Karl-Heinz Herbinger [Allemagne] ; Ingrid Hanus [Allemagne] ; Mirjam Schunk [Allemagne] ; Marcus Beissner [Allemagne] ; Frank Von Sonnenburg [Allemagne] ; Thomas Löscher [Allemagne] ; Gisela Bretzel [Allemagne] ; Michael Hoelscher [Allemagne] ; Hans Dieter Nothdurft [Allemagne] ; Kristina Lydia Huber [Allemagne]Source :
- The American journal of tropical medicine and hygiene [ 1476-1645 ] ; 2016.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Afrique (MeSH), Allemagne (MeSH), Amérique latine (MeSH), Asie (MeSH), Dysenterie bacillaire (métabolisme), Enfant (MeSH), Enfant d'âge préscolaire (MeSH), Entérite (métabolisme), Facteurs sexuels (MeSH), Femelle (MeSH), Fièvre paratyphoïde (métabolisme), Fièvre typhoïde (métabolisme), Grippe humaine (métabolisme), Humains (MeSH), Infection à Entamoeba (métabolisme), Infections bactériennes (métabolisme), Infections à Campylobacter (métabolisme), Infections à cytomégalovirus (métabolisme), Infections à virus Epstein-Barr (métabolisme), Jeune adulte (MeSH), Maladies parasitaires (métabolisme), Maladies virales (métabolisme), Mâle (MeSH), Nourrisson (MeSH), Paludisme (métabolisme), Protéine C-réactive (métabolisme), Rickettsioses (métabolisme), Salmonelloses (métabolisme), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Voyage (MeSH), Études cas-témoins (MeSH), Études transversales (MeSH).
- MESH :
- métabolisme : Dysenterie bacillaire, Entérite, Fièvre paratyphoïde, Fièvre typhoïde, Grippe humaine, Infection à Entamoeba, Infections bactériennes, Infections à Campylobacter, Infections à cytomégalovirus, Infections à virus Epstein-Barr, Maladies parasitaires, Maladies virales, Paludisme, Protéine C-réactive, Rickettsioses, Salmonelloses.
- Adolescent, Adulte, Adulte d'âge moyen, Afrique, Allemagne, Amérique latine, Asie, Enfant, Enfant d'âge préscolaire, Facteurs sexuels, Femelle, Humains, Jeune adulte, Mâle, Nourrisson, Sujet âgé, Sujet âgé de 80 ans ou plus, Voyage, Études cas-témoins, Études transversales.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Africa (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Asia (MeSH), Bacterial Infections (metabolism), C-Reactive Protein (metabolism), Campylobacter Infections (metabolism), Case-Control Studies (MeSH), Child (MeSH), Child, Preschool (MeSH), Cross-Sectional Studies (MeSH), Cytomegalovirus Infections (metabolism), Dysentery, Bacillary (metabolism), Entamoebiasis (metabolism), Enteritis (metabolism), Epstein-Barr Virus Infections (metabolism), Female (MeSH), Germany (MeSH), Humans (MeSH), Infant (MeSH), Influenza, Human (metabolism), Latin America (MeSH), Malaria (metabolism), Male (MeSH), Middle Aged (MeSH), Parasitic Diseases (metabolism), Paratyphoid Fever (metabolism), Rickettsia Infections (metabolism), Salmonella Infections (metabolism), Sex Factors (MeSH), Travel (MeSH), Typhoid Fever (metabolism), Virus Diseases (metabolism), Young Adult (MeSH).
- MESH :
- chemical , metabolism : C-Reactive Protein.
- metabolism : Bacterial Infections, Campylobacter Infections, Cytomegalovirus Infections, Dysentery, Bacillary, Entamoebiasis, Enteritis, Epstein-Barr Virus Infections, Influenza, Human, Malaria, Parasitic Diseases, Paratyphoid Fever, Rickettsia Infections, Salmonella Infections, Typhoid Fever, Virus Diseases.
- Adolescent, Adult, Africa, Aged, Aged, 80 and over, Asia, Case-Control Studies, Child, Child, Preschool, Cross-Sectional Studies, Female, Germany, Humans, Infant, Latin America, Male, Middle Aged, Sex Factors, Travel, Young Adult.
Abstract
The present controlled cross-sectional study aimed to assess elevated values of C-reactive protein (CRP), a positive acute-phase protein, induced by imported infectious diseases (IDs) seen in patients consulting the University of Munich (1999-2015) after being in the tropics/subtropics. The analysis investigated data sets from 11,079 diseased German travelers (cases) returning from Latin America (1,986), Africa (3,387), and Asia (5,706), and from 714 healthy Germans who had not recently traveled (controls). The proportions of elevated values of CRP (> 0.5 mg/dL) were significantly larger among cases (44.3%) than among controls (20.7%). Among cases, this proportion was largest among males (49.2%) in comparison to females (39.9%), among travelers with short travel duration of 1-14 days (49.6%) in comparison to travelers with a travel duration of > 180 days (30.8%), and with travel destination in Africa (47.0%) in comparison to Asia (44.2%) and Latin America (39.9%), among all-inclusive travelers (47.4%) in comparison to business travelers (46.7%) and backpackers (44.1%), and among patients presenting with fever (70.9%) and arthralgia (54.3%). The study identified various imported IDs with significantly larger proportions of elevated values of CRP including viral (cytomegalovirus infection [94.7%], influenza [88.9%], infectious mononucleosis [71.8%]), bacterial (typhoid fever [100%], paratyphoid fever [92.9%], shigellosis [76.8%], rickettsiosis [74.2%], Salmonella enteritis [71.3%], Campylobacter infection [68.7%]), and protozoan (vivax malaria [100%], ovale malaria [100%], falciparum malaria [95.4%], noninvasive Entamoeba infection [65.9%]) IDs. This study demonstrates that elevated values of CRP can be a useful laboratory finding for travelers returning from the tropics/subtropics, as these findings are typically caused mainly by certain imported bacterial IDs, but also by viral and protozoan IDs.
DOI: 10.4269/ajtmh.16-0387
PubMed: 27527624
PubMed Central: PMC5062804
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics.</title><author><name sortKey="Herbinger, Karl Heinz" sort="Herbinger, Karl Heinz" uniqKey="Herbinger K" first="Karl-Heinz" last="Herbinger">Karl-Heinz Herbinger</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. herbinger@lrz.uni-muenchen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Hanus, Ingrid" sort="Hanus, Ingrid" uniqKey="Hanus I" first="Ingrid" last="Hanus">Ingrid Hanus</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Schunk, Mirjam" sort="Schunk, Mirjam" uniqKey="Schunk M" first="Mirjam" last="Schunk">Mirjam Schunk</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Beissner, Marcus" sort="Beissner, Marcus" uniqKey="Beissner M" first="Marcus" last="Beissner">Marcus Beissner</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Von Sonnenburg, Frank" sort="Von Sonnenburg, Frank" uniqKey="Von Sonnenburg F" first="Frank" last="Von Sonnenburg">Frank Von Sonnenburg</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Loscher, Thomas" sort="Loscher, Thomas" uniqKey="Loscher T" first="Thomas" last="Löscher">Thomas Löscher</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Bretzel, Gisela" sort="Bretzel, Gisela" uniqKey="Bretzel G" first="Gisela" last="Bretzel">Gisela Bretzel</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Hoelscher, Michael" sort="Hoelscher, Michael" uniqKey="Hoelscher M" first="Michael" last="Hoelscher">Michael Hoelscher</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. German Centre for Infection Research (DZIF), Partner Site Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. German Centre for Infection Research (DZIF), Partner Site Munich</wicri:regionArea><wicri:noRegion>Partner Site Munich</wicri:noRegion><orgName type="university">Université Louis-et-Maximilien de Munich</orgName><placeName><settlement type="city">Munich</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region></placeName></affiliation></author><author><name sortKey="Nothdurft, Hans Dieter" sort="Nothdurft, Hans Dieter" uniqKey="Nothdurft H" first="Hans Dieter" last="Nothdurft">Hans Dieter Nothdurft</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Huber, Kristina Lydia" sort="Huber, Kristina Lydia" uniqKey="Huber K" first="Kristina Lydia" last="Huber">Kristina Lydia Huber</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27527624</idno><idno type="pmid">27527624</idno><idno type="doi">10.4269/ajtmh.16-0387</idno><idno type="pmc">PMC5062804</idno><idno type="wicri:Area/Main/Corpus">000083</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000083</idno><idno type="wicri:Area/Main/Curation">000083</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000083</idno><idno type="wicri:Area/Main/Exploration">000083</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics.</title><author><name sortKey="Herbinger, Karl Heinz" sort="Herbinger, Karl Heinz" uniqKey="Herbinger K" first="Karl-Heinz" last="Herbinger">Karl-Heinz Herbinger</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. herbinger@lrz.uni-muenchen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Hanus, Ingrid" sort="Hanus, Ingrid" uniqKey="Hanus I" first="Ingrid" last="Hanus">Ingrid Hanus</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Schunk, Mirjam" sort="Schunk, Mirjam" uniqKey="Schunk M" first="Mirjam" last="Schunk">Mirjam Schunk</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Beissner, Marcus" sort="Beissner, Marcus" uniqKey="Beissner M" first="Marcus" last="Beissner">Marcus Beissner</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Von Sonnenburg, Frank" sort="Von Sonnenburg, Frank" uniqKey="Von Sonnenburg F" first="Frank" last="Von Sonnenburg">Frank Von Sonnenburg</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Loscher, Thomas" sort="Loscher, Thomas" uniqKey="Loscher T" first="Thomas" last="Löscher">Thomas Löscher</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Bretzel, Gisela" sort="Bretzel, Gisela" uniqKey="Bretzel G" first="Gisela" last="Bretzel">Gisela Bretzel</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Hoelscher, Michael" sort="Hoelscher, Michael" uniqKey="Hoelscher M" first="Michael" last="Hoelscher">Michael Hoelscher</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. German Centre for Infection Research (DZIF), Partner Site Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. German Centre for Infection Research (DZIF), Partner Site Munich</wicri:regionArea><wicri:noRegion>Partner Site Munich</wicri:noRegion><orgName type="university">Université Louis-et-Maximilien de Munich</orgName><placeName><settlement type="city">Munich</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region></placeName></affiliation></author><author><name sortKey="Nothdurft, Hans Dieter" sort="Nothdurft, Hans Dieter" uniqKey="Nothdurft H" first="Hans Dieter" last="Nothdurft">Hans Dieter Nothdurft</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Huber, Kristina Lydia" sort="Huber, Kristina Lydia" uniqKey="Huber K" first="Kristina Lydia" last="Huber">Kristina Lydia Huber</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author></analytic><series><title level="j">The American journal of tropical medicine and hygiene</title><idno type="eISSN">1476-1645</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Africa (MeSH)</term><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Asia (MeSH)</term><term>Bacterial Infections (metabolism)</term><term>C-Reactive Protein (metabolism)</term><term>Campylobacter Infections (metabolism)</term><term>Case-Control Studies (MeSH)</term><term>Child (MeSH)</term><term>Child, Preschool (MeSH)</term><term>Cross-Sectional Studies (MeSH)</term><term>Cytomegalovirus Infections (metabolism)</term><term>Dysentery, Bacillary (metabolism)</term><term>Entamoebiasis (metabolism)</term><term>Enteritis (metabolism)</term><term>Epstein-Barr Virus Infections (metabolism)</term><term>Female (MeSH)</term><term>Germany (MeSH)</term><term>Humans (MeSH)</term><term>Infant (MeSH)</term><term>Influenza, Human (metabolism)</term><term>Latin America (MeSH)</term><term>Malaria (metabolism)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Parasitic Diseases (metabolism)</term><term>Paratyphoid Fever (metabolism)</term><term>Rickettsia Infections (metabolism)</term><term>Salmonella Infections (metabolism)</term><term>Sex Factors (MeSH)</term><term>Travel (MeSH)</term><term>Typhoid Fever (metabolism)</term><term>Virus Diseases (metabolism)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Afrique (MeSH)</term><term>Allemagne (MeSH)</term><term>Amérique latine (MeSH)</term><term>Asie (MeSH)</term><term>Dysenterie bacillaire (métabolisme)</term><term>Enfant (MeSH)</term><term>Enfant d'âge préscolaire (MeSH)</term><term>Entérite (métabolisme)</term><term>Facteurs sexuels (MeSH)</term><term>Femelle (MeSH)</term><term>Fièvre paratyphoïde (métabolisme)</term><term>Fièvre typhoïde (métabolisme)</term><term>Grippe humaine (métabolisme)</term><term>Humains (MeSH)</term><term>Infection à Entamoeba (métabolisme)</term><term>Infections bactériennes (métabolisme)</term><term>Infections à Campylobacter (métabolisme)</term><term>Infections à cytomégalovirus (métabolisme)</term><term>Infections à virus Epstein-Barr (métabolisme)</term><term>Jeune adulte (MeSH)</term><term>Maladies parasitaires (métabolisme)</term><term>Maladies virales (métabolisme)</term><term>Mâle (MeSH)</term><term>Nourrisson (MeSH)</term><term>Paludisme (métabolisme)</term><term>Protéine C-réactive (métabolisme)</term><term>Rickettsioses (métabolisme)</term><term>Salmonelloses (métabolisme)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Voyage (MeSH)</term><term>Études cas-témoins (MeSH)</term><term>Études transversales (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>C-Reactive Protein</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Bacterial Infections</term><term>Campylobacter Infections</term><term>Cytomegalovirus Infections</term><term>Dysentery, Bacillary</term><term>Entamoebiasis</term><term>Enteritis</term><term>Epstein-Barr Virus Infections</term><term>Influenza, Human</term><term>Malaria</term><term>Parasitic Diseases</term><term>Paratyphoid Fever</term><term>Rickettsia Infections</term><term>Salmonella Infections</term><term>Typhoid Fever</term><term>Virus Diseases</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Dysenterie bacillaire</term><term>Entérite</term><term>Fièvre paratyphoïde</term><term>Fièvre typhoïde</term><term>Grippe humaine</term><term>Infection à Entamoeba</term><term>Infections bactériennes</term><term>Infections à Campylobacter</term><term>Infections à cytomégalovirus</term><term>Infections à virus Epstein-Barr</term><term>Maladies parasitaires</term><term>Maladies virales</term><term>Paludisme</term><term>Protéine C-réactive</term><term>Rickettsioses</term><term>Salmonelloses</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Africa</term><term>Aged</term><term>Aged, 80 and over</term><term>Asia</term><term>Case-Control Studies</term><term>Child</term><term>Child, Preschool</term><term>Cross-Sectional Studies</term><term>Female</term><term>Germany</term><term>Humans</term><term>Infant</term><term>Latin America</term><term>Male</term><term>Middle Aged</term><term>Sex Factors</term><term>Travel</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Afrique</term><term>Allemagne</term><term>Amérique latine</term><term>Asie</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Facteurs sexuels</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Nourrisson</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Voyage</term><term>Études cas-témoins</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The present controlled cross-sectional study aimed to assess elevated values of C-reactive protein (CRP), a positive acute-phase protein, induced by imported infectious diseases (IDs) seen in patients consulting the University of Munich (1999-2015) after being in the tropics/subtropics. The analysis investigated data sets from 11,079 diseased German travelers (cases) returning from Latin America (1,986), Africa (3,387), and Asia (5,706), and from 714 healthy Germans who had not recently traveled (controls). The proportions of elevated values of CRP (> 0.5 mg/dL) were significantly larger among cases (44.3%) than among controls (20.7%). Among cases, this proportion was largest among males (49.2%) in comparison to females (39.9%), among travelers with short travel duration of 1-14 days (49.6%) in comparison to travelers with a travel duration of > 180 days (30.8%), and with travel destination in Africa (47.0%) in comparison to Asia (44.2%) and Latin America (39.9%), among all-inclusive travelers (47.4%) in comparison to business travelers (46.7%) and backpackers (44.1%), and among patients presenting with fever (70.9%) and arthralgia (54.3%). The study identified various imported IDs with significantly larger proportions of elevated values of CRP including viral (cytomegalovirus infection [94.7%], influenza [88.9%], infectious mononucleosis [71.8%]), bacterial (typhoid fever [100%], paratyphoid fever [92.9%], shigellosis [76.8%], rickettsiosis [74.2%], Salmonella enteritis [71.3%], Campylobacter infection [68.7%]), and protozoan (vivax malaria [100%], ovale malaria [100%], falciparum malaria [95.4%], noninvasive Entamoeba infection [65.9%]) IDs. This study demonstrates that elevated values of CRP can be a useful laboratory finding for travelers returning from the tropics/subtropics, as these findings are typically caused mainly by certain imported bacterial IDs, but also by viral and protozoan IDs.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27527624</PMID><DateCompleted><Year>2017</Year><Month>05</Month><Day>25</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1476-1645</ISSN><JournalIssue CitedMedium="Internet"><Volume>95</Volume><Issue>4</Issue><PubDate><Year>2016</Year><Month>Oct</Month><Day>05</Day></PubDate></JournalIssue><Title>The American journal of tropical medicine and hygiene</Title><ISOAbbreviation>Am. J. Trop. Med. Hyg.</ISOAbbreviation></Journal><ArticleTitle>Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics.</ArticleTitle><Pagination><MedlinePgn>938-944</MedlinePgn></Pagination><Abstract><AbstractText>The present controlled cross-sectional study aimed to assess elevated values of C-reactive protein (CRP), a positive acute-phase protein, induced by imported infectious diseases (IDs) seen in patients consulting the University of Munich (1999-2015) after being in the tropics/subtropics. The analysis investigated data sets from 11,079 diseased German travelers (cases) returning from Latin America (1,986), Africa (3,387), and Asia (5,706), and from 714 healthy Germans who had not recently traveled (controls). The proportions of elevated values of CRP (> 0.5 mg/dL) were significantly larger among cases (44.3%) than among controls (20.7%). Among cases, this proportion was largest among males (49.2%) in comparison to females (39.9%), among travelers with short travel duration of 1-14 days (49.6%) in comparison to travelers with a travel duration of > 180 days (30.8%), and with travel destination in Africa (47.0%) in comparison to Asia (44.2%) and Latin America (39.9%), among all-inclusive travelers (47.4%) in comparison to business travelers (46.7%) and backpackers (44.1%), and among patients presenting with fever (70.9%) and arthralgia (54.3%). The study identified various imported IDs with significantly larger proportions of elevated values of CRP including viral (cytomegalovirus infection [94.7%], influenza [88.9%], infectious mononucleosis [71.8%]), bacterial (typhoid fever [100%], paratyphoid fever [92.9%], shigellosis [76.8%], rickettsiosis [74.2%], Salmonella enteritis [71.3%], Campylobacter infection [68.7%]), and protozoan (vivax malaria [100%], ovale malaria [100%], falciparum malaria [95.4%], noninvasive Entamoeba infection [65.9%]) IDs. This study demonstrates that elevated values of CRP can be a useful laboratory finding for travelers returning from the tropics/subtropics, as these findings are typically caused mainly by certain imported bacterial IDs, but also by viral and protozoan IDs.</AbstractText><CopyrightInformation>© The American Society of Tropical Medicine and Hygiene.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Herbinger</LastName><ForeName>Karl-Heinz</ForeName><Initials>KH</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. herbinger@lrz.uni-muenchen.de.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hanus</LastName><ForeName>Ingrid</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schunk</LastName><ForeName>Mirjam</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beissner</LastName><ForeName>Marcus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>von Sonnenburg</LastName><ForeName>Frank</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Löscher</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bretzel</LastName><ForeName>Gisela</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hoelscher</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany. German Centre for Infection Research (DZIF), Partner Site Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nothdurft</LastName><ForeName>Hans Dieter</ForeName><Initials>HD</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huber</LastName><ForeName>Kristina Lydia</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Division of Infectious Diseases and Tropical Medicine (DITM), Medical Center of the University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>08</Month><Day>15</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Am J Trop Med Hyg</MedlineTA><NlmUniqueID>0370507</NlmUniqueID><ISSNLinking>0002-9637</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>9007-41-4</RegistryNumber><NameOfSubstance UI="D002097">C-Reactive Protein</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000349" MajorTopicYN="N">Africa</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001208" MajorTopicYN="N">Asia</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001424" MajorTopicYN="N">Bacterial Infections</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002097" MajorTopicYN="N">C-Reactive Protein</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002169" MajorTopicYN="N">Campylobacter Infections</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003586" MajorTopicYN="N">Cytomegalovirus Infections</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004405" MajorTopicYN="N">Dysentery, Bacillary</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004749" MajorTopicYN="N">Entamoebiasis</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004751" MajorTopicYN="N">Enteritis</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020031" MajorTopicYN="N">Epstein-Barr Virus Infections</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N">Germany</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007843" MajorTopicYN="N">Latin America</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008288" MajorTopicYN="N">Malaria</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010272" MajorTopicYN="N">Parasitic Diseases</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010284" MajorTopicYN="N">Paratyphoid Fever</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012282" MajorTopicYN="N">Rickettsia Infections</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012480" MajorTopicYN="N">Salmonella Infections</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012737" MajorTopicYN="N">Sex Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014195" MajorTopicYN="Y">Travel</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014435" MajorTopicYN="N">Typhoid Fever</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014777" MajorTopicYN="N">Virus Diseases</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>05</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>06</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>8</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>5</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>8</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27527624</ArticleId><ArticleId IdType="pii">ajtmh.16-0387</ArticleId><ArticleId IdType="doi">10.4269/ajtmh.16-0387</ArticleId><ArticleId IdType="pmc">PMC5062804</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Adv Intern Med. 1982;27:345-72</Citation><ArticleIdList><ArticleId IdType="pubmed">7041546</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Chem. 1993 Feb;39(2):293-7</Citation><ArticleIdList><ArticleId IdType="pubmed">8381732</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 1996 Jun 15;156(12):4691-6</Citation><ArticleIdList><ArticleId IdType="pubmed">8648114</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Trop Med Hyg. 2016 Aug 3;95(2):481-7</Citation><ArticleIdList><ArticleId IdType="pubmed">27215300</ArticleId></ArticleIdList></Reference><Reference><Citation>Glycoconj J. 2006 May;23(3-4):233-40</Citation><ArticleIdList><ArticleId IdType="pubmed">16691506</ArticleId></ArticleIdList></Reference><Reference><Citation>Infection. 2012 Aug;40(4):373-9</Citation><ArticleIdList><ArticleId IdType="pubmed">22350868</ArticleId></ArticleIdList></Reference><Reference><Citation>Malar J. 2014 Apr 23;13:155</Citation><ArticleIdList><ArticleId IdType="pubmed">24758172</ArticleId></ArticleIdList></Reference><Reference><Citation>J Travel Med. 2012 May-Jun;19(3):150-7</Citation><ArticleIdList><ArticleId IdType="pubmed">22530821</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Chim Acta. 2002 Aug;322(1-2):163-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12104096</ArticleId></ArticleIdList></Reference><Reference><Citation>Trop Med Int Health. 2011 Nov;16(11):1457-64</Citation><ArticleIdList><ArticleId IdType="pubmed">21767336</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Chemother. 2002 Mar;8(1):76-80</Citation><ArticleIdList><ArticleId IdType="pubmed">11957124</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem J. 1997 Oct 15;327 ( Pt 2):425-9</Citation><ArticleIdList><ArticleId IdType="pubmed">9359411</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunol Res. 2013 May;56(1):131-42</Citation><ArticleIdList><ArticleId IdType="pubmed">23371836</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Trop Med Hyg. 2016 Jun 1;94(6):1385-91</Citation><ArticleIdList><ArticleId IdType="pubmed">27068397</ArticleId></ArticleIdList></Reference><Reference><Citation>Autoimmunity. 2013 Aug;46(5):347-50</Citation><ArticleIdList><ArticleId IdType="pubmed">23600950</ArticleId></ArticleIdList></Reference><Reference><Citation>Crit Rev Clin Lab Sci. 2011 Jul-Aug;48(4):155-70</Citation><ArticleIdList><ArticleId IdType="pubmed">22035340</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Trop Med Hyg. 2016 Apr;94(4):757-66</Citation><ArticleIdList><ArticleId IdType="pubmed">26903611</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Infect. 2011 Aug;17(8):1194-200</Citation><ArticleIdList><ArticleId IdType="pubmed">21054662</ArticleId></ArticleIdList></Reference><Reference><Citation>Adv Biomed Res. 2012;1:41</Citation><ArticleIdList><ArticleId IdType="pubmed">23326772</ArticleId></ArticleIdList></Reference><Reference><Citation>Trans R Soc Trop Med Hyg. 1996 Jan-Feb;90(1):10-4</Citation><ArticleIdList><ArticleId IdType="pubmed">8730300</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2031-41</Citation><ArticleIdList><ArticleId IdType="pubmed">15653761</ArticleId></ArticleIdList></Reference><Reference><Citation>Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):182-6</Citation><ArticleIdList><ArticleId IdType="pubmed">8036666</ArticleId></ArticleIdList></Reference><Reference><Citation>Adv Immunol. 1983;34:141-212</Citation><ArticleIdList><ArticleId IdType="pubmed">6356809</ArticleId></ArticleIdList></Reference><Reference><Citation>Infection. 2013 Dec;41(6):1079-87</Citation><ArticleIdList><ArticleId IdType="pubmed">24014235</ArticleId></ArticleIdList></Reference><Reference><Citation>Structure. 1999 Feb 15;7(2):169-77</Citation><ArticleIdList><ArticleId IdType="pubmed">10368284</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 1930 Sep 30;52(4):561-71</Citation><ArticleIdList><ArticleId IdType="pubmed">19869788</ArticleId></ArticleIdList></Reference><Reference><Citation>Infection. 2011 Dec;39(6):527-35</Citation><ArticleIdList><ArticleId IdType="pubmed">21717146</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country><region><li>Bavière</li><li>District de Haute-Bavière</li></region><settlement><li>Munich</li></settlement><orgName><li>Université Louis-et-Maximilien de Munich</li></orgName></list><tree><country name="Allemagne"><region name="Bavière"><name sortKey="Herbinger, Karl Heinz" sort="Herbinger, Karl Heinz" uniqKey="Herbinger K" first="Karl-Heinz" last="Herbinger">Karl-Heinz Herbinger</name></region><name sortKey="Beissner, Marcus" sort="Beissner, Marcus" uniqKey="Beissner M" first="Marcus" last="Beissner">Marcus Beissner</name><name sortKey="Bretzel, Gisela" sort="Bretzel, Gisela" uniqKey="Bretzel G" first="Gisela" last="Bretzel">Gisela Bretzel</name><name sortKey="Hanus, Ingrid" sort="Hanus, Ingrid" uniqKey="Hanus I" first="Ingrid" last="Hanus">Ingrid Hanus</name><name sortKey="Hoelscher, Michael" sort="Hoelscher, Michael" uniqKey="Hoelscher M" first="Michael" last="Hoelscher">Michael Hoelscher</name><name sortKey="Huber, Kristina Lydia" sort="Huber, Kristina Lydia" uniqKey="Huber K" first="Kristina Lydia" last="Huber">Kristina Lydia Huber</name><name sortKey="Loscher, Thomas" sort="Loscher, Thomas" uniqKey="Loscher T" first="Thomas" last="Löscher">Thomas Löscher</name><name sortKey="Nothdurft, Hans Dieter" sort="Nothdurft, Hans Dieter" uniqKey="Nothdurft H" first="Hans Dieter" last="Nothdurft">Hans Dieter Nothdurft</name><name sortKey="Schunk, Mirjam" sort="Schunk, Mirjam" uniqKey="Schunk M" first="Mirjam" last="Schunk">Mirjam Schunk</name><name sortKey="Von Sonnenburg, Frank" sort="Von Sonnenburg, Frank" uniqKey="Von Sonnenburg F" first="Frank" last="Von Sonnenburg">Frank Von Sonnenburg</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeAllemagneV4/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000100 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000100 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= GrippeAllemagneV4
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:27527624
|texte= Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27527624" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a GrippeAllemagneV4
| This area was generated with Dilib version V0.6.35. |  |